Table 1.

Western blot analysis of MMP and tight junction protein expression levels in brain capillaries isolated from rats after SE (Fig. 2A)^a

Protein	Control	Pilo	SE
MMP-2	100 ± 5.1	95 ± 6.2	132 ± 5.2*
MMP-9	100 ± 5.1	93 ± 5.2	125 ± 7.5*
ZO-1	100 ± 13	83 ± 11.7	29 ± 3.9*
Occludin	100 ± 2	108 ± 2	43 ± 0.6*
Claudin-1	100 ± 5.5	77 ± 10.9	52 ± 6.6*
Claudin-5	100 ± 3.9	94 ± 3.5	73 ± 2.6*

^aData were normalized to β-actin levels; values are percentage control ± SD (n = 3).

*p < 0.05, each endpoint versus control (Dunnett's many-to-one t test).