TABLE 1.

Sample Characteristics

Characteristic	Control	MDD nonremitter	MDD remitter	P
Sample size	31	14	12	—
Age (y)	32.62 ± 11.27	37.03 ± 13.47	36.67 ± 13.48	0.54*
HDRS-24 pretreatment	1.68 ± 2.41	25.43 ± 2.26	24.08 ± 6.23	0.59†
HDRS-24 posttreatment	—	17.57 ± 3.90	5.33 ± 3.06	0.001†
HDRS-17 scores (inclusion criteria)	1.42 ± 1.28	19.07 ± 4.60	19.08 ± 5.03	1.0†
Beck Depression Inventory	1.29 ± 1.69	26.71 ± 10.04	22.42 ± 10.47	0.30†
Beck Hopelessness Scale	1.32 ± 1.87	11.36 ± 5.25	7.8 ± 6.38	0.26†
Age of onset	—	25.5 ± 13.5	24.17 ± 12.61	0.66†
Number of depressive episodes	—	13.85 ± 30.50	19.33 ± 37.47	0.69†
Number of first-degree relatives with depression	4 ± 2	4 ± 2	3 ± 2	0.48*
Percentage with comorbid anxiety	—	7%	8%	0.96†
Percentage female	52%	71%	58%	0.47†
Percentage of smokers	6.5	25	7.1	0.25*
Free fraction (fP)	0.12 ± 0.3	0.1 ± 0.01	0.1 ± 0.02	0.02*
Reference region binding	10.50 ± 2.19	10.64 ± 1.41	9.41 ± 1.39	0.07*

^*Statistics comparing all groups.

^†Statistics comparing nonremitters and remitters, only.