Fig. 1.

Proliferative behavior of hMuStem cells^FBS cultured in vitro in HS-supplemented or hPL-supplemented medium. a hMuStem cells^FBS (n = 3, donors #1–#3) cultured for 14 days in growth medium (GM) supplemented with either 10% FBS, 10% HS, or 10% hPL. Proliferation rates determined as mean cumulative population doubling (CPD) number, expressed as percentage of corresponding values obtained for FBS-GM (*p < 0.05, Friedman test). b hMuStem cells^HS (n = 3, donors #4–#6) cultured for 6 days in GM supplemented with either 10% HS or 10% hPL, in presence or absence of 10 ng/ml bFGF. Proliferation rates determined as CPD (***p < 0.001, LME model followed by Tukey’s post-hoc test). FBS fetal bovine serum, HS human serum, hPL human platelet lysate, bFGF basic fibroblast growth factor