Table 3.
Longitudinal volume changes (in measured total intracranial volume (mTIV) ratio) within the chemotherapy group and the healthy control group
| Chemotherapy group (n = 16) | Healthy control group (n = 14) | p comparing groups* | |||
|---|---|---|---|---|---|
| changes in mTIV ratio (SD) | p value | changes in mTIV ratio (SD) | p value | ||
| Total white matter | 1.65 (3.63) | 0.06 | 0.90 (2.91) | 0.32 | 0.54 |
| Total gray matter | −2.05 (3.38) | 0.02 | −0.99 (3.18) | 0.27 | 0.38 |
| Frontal lobe | −0.33 (0.39) | 0.003 | −0.27 (0.44) | 0.02 | 0.68 |
| Temporal lobe | −0.09 (0.31) | 0.16 | 0.08 (0.16) | 0.25 | 0.08 |
| Parietal lobe | −0.07 (0.27) | 0.27 | −0.08 (0.22) | 0.23 | 0.89 |
| Occipital lobe | 0.01 (0.18) | 0.77 | −0.02 (0.14) | 0.65 | 0.60 |
*p values from comparison of volume changes between the two groups (group-by-time interaction)