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Time line demonstrating injection and mating schedules. Injections were given once a day on day 0; days 0 and 1; or days 0, 1, and 2. Alterations in mating timing allow for implantation to occur during T regulatory cell (Treg) nadir in the peripheral blood (A) or uterine tissue (B). (C) Time line of injection, mating, and adoptive transfer of Tregs.
