Figure 5.

Effect of hormones on tissue thickness. H&E stained cross-sections of (A) VEC PT or (B) VEC-FT tissues. Tissue thickness was measured after 11 days of culture in medium supplemented with hormones. Thickness was measured at 10 different locations and an average thickness was calculated. Estradiol treatment resulted in increased tissue thickness in the partial thickness model and enhanced cornification (arrow) in the full thickness tissue. Progesterone decreased tissue thickness in partial thickness model, but did not significantly alter tissue thickness in the full thickness tissue model.