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Fetal and placental weights were reduced in pregnant rats exposed to cigarette smoke, nicotine, and bupropion. The animals were killed on gestational day (GD) 20, and (A) fetal, (B) placental junctional zone, and (C) placental labyrinth zone weights were measured. Data are expressed as mean ± standard error of the mean (SEM) of 6 rats in each group. Bars with different alphabet superscripts differ significantly (P < .05).
