Maternal cigarette smoke, nicotine, and bupropion exposure dysregulates messenger RNA (mRNA) of transient receptor potential channels (Trpc1, Trpc2, Trpc3, Trpc4, Trpc6, and Trpc7) in the neonatal heart. Quantitation of fold change in Trpc was normalized relative to β-actin levels. Values are given as means ± standard error of the mean (sem) of 6 rats in each group. Bars with different alphabet superscripts differ significantly (P < .05).