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Maternal smoke and nicotine but not bupropion exposure increased blood pressure in adult offspring. Heart rate was significantly higher in smoking, nicotine, and bupropion offspring compared to controls. (A) Blood pressure and (B) heart rate were measured 24 hours per day by telemetry at 6 months of age for 5 days. Values are given as means ± standard error of the mean (sem) of 6 rats in each group. Bars with different alphabet superscripts differ significantly (P < .05).
