Table 1.

Vinylsulfone Ameliorates High Glucose-Induced Neural Tube Defects.

Group	Total Embryos	Embryos With NTDs	NTD Rate, %
NG	15	1	6.67
NG + VS (20 μmol/L)	15	2	13.33
HGa	15	10	66.67
HG + VS (10 μmol/L)	15	5	33.33
HG + VS (20 μmol/L)	15	3	20.00

Abbreviations: VS, vinylsulfone; HG, high glucose (16.7 mmol/L); NG, normal glucose (5 mmol/L); NTDs, neural tube defects.

^aHG group is statistically significant from the NG, NG + VS (20 μmol/L), HG + VS (10 μmol/L), and HG + VS (20 μmol/L) groups. Statistical significance was analyzed by χ² test.