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. 2015 Oct 4;23(4):542–548. doi: 10.1177/1933719115607998

Figure 4.

Figure 4.

Vascular reactivity to Ang II in omental arteries obtained from women with preeclampsia. The vasoconstrictive response to Ang II was significantly enhanced in preeclamptic omental arteries (n = 5) as compared with normal pregnant arteries (n = 11; panel A). The enhanced response of preeclamptic arteries was abolished by removal of the endothelium (n = 2, panel A) or coperfusion with inhibitors of PAR-1 (n = 5), ROCK (n = 5), or ET-1 (n = 4; panel B). a P < .05, b P < .01, c P < .001, d P < .0001 compared to other treatments for that dose. Ang II indicates angiotensin II; ET-1, endothelin 1; NS, nonsignificant for treatment effects; PAR, protease-activated receptor; ROCK, RhoA kinase.