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. 2018 Apr 26;9:263. doi: 10.3389/fneur.2018.00263

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Copyright © 2018 Rolf, Damoiseaux, Huitinga, Kimenai, van den Ouweland, Hupperts and Smolders.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of vitamin D₃ supplements on serum 25(OH)D levels. (A) Within group comparisons of serum 25(OH)D levels at T0 (baseline) and T1 (week 16) in the vitamin D₃ supplemented arm (n = 22), (B) within group comparisons of serum 25(OH)D levels at T0 and T1 in the placebo arm (n = 19), (C) between group comparisons of the serum 25(OH)D level differences between T1 and T0. (D) group comparisons of serum 25(OH)D levels < and >100 nmol/L at T0 and T1. p-Values calculated with (A,B) Wilcoxon signed ranks, (C) Mann–Whitney U or (D) χ² test.