Table 2.
Overview of adverse events in participants who received the allocated intervention.
| Adverse event type | All (n) | Vitamin D3 (n) | Placebo (n) |
|---|---|---|---|
| Relapse | 1 | 1 | 1 |
| Hypercalciuria | 5 | 2 | 3 |
| Hypocalcemia | 0 | 0 | 0 |
| Infections | |||
| Urinary tract infection | 6 | 3 | 3 |
| Pharyngitis | 1 | 1 | 0 |
| Ear infection | 2 | 1 | 1 |
| Herpes zoster infection | 1 | 1 | 0 |
| Influenza | 3 | 0 | 3 |
| Upper respiratory tract infection | 4 | 1 | 3 |
| Gastrointestinal | |||
| Abdominal pain | 1 | 0 | 1 |
| Stomach discomfort | 1 | 0 | 1 |
| Cardiovascular | |||
| Hypertension | 1 | 0 | 1 |
| Hypercholesterolemia | 1 | 0 | 1 |
| Cold extremities | 1 | 0 | 1 |
| Musculoskeletal | |||
| Lumbago | 1 | 0 | 1 |
| Leg pains | 1 | 1 | 0 |
| Ruptured ankle ligaments | 1 | 0 | 1 |
| Achilles tendinosis | 1 | 0 | 1 |
| Lateral epicondylitis | 1 | 0 | 1 |
| Other | |||
| Pregnancy | 1 | 0 | 1 |
| Iron deficiency | 1 | 0 | 1 |
| Headaches | 2 | 2 | 0 |
| Fatigue | 2 | 1 | 1 |
| Dizziness | 2 | 2 | 0 |
| Axillary pains | 1 | 1 | 0 |
| Globus/tingling sensations during swallowing | 2 | 2 | 0 |
| Mood swings | 2 | 2 | 0 |
| Suicidal thoughts | 1 | 0 | 1 |