Table 3.
Within and between group comparisons for circadian cortisol levels.
| Vitamin D3 (n = 22) |
Placebo (n = 19) |
||||||
|---|---|---|---|---|---|---|---|
| T0 M (Q1–Q3) |
T1 M (Q1–Q3) |
p-Value* | T0 M (Q1–Q3) |
T1 M (Q1–Q3) |
p-Value* | p-Value** | |
| AUC of CDC | 13.11 (9.24–15.05) | 11.4 (9.21–14.04) | 0.357 | 10.14 (8.49–12.34) | 9.92 (7.93–12.04) | 0.344 | 0.915 |
| Slope of CDC | −0.23 (−0.27 to −0.19) | −0.26 (−0.28 to −0.23) | 0.159 | −0.24 (−0.29 to −0.18) | −0.23 (−0.29 to −0.20) | 0.778 | 0.347 |
| AUC of CAR | 39.16 (27.41–42.07) | 33.37 (26.75–38.08) | 0.095 | 33.90 (25.92–44.61) | 35.00 (25.46–49.23) | 0.260 | 0.044 |
AUC, area under the curve; CDC, cortisol day curve; CAR, cortisol awakening response; T0 = baseline; T1 = week 16; M = median; Q1–Q3 = 25th–75th percentile.
*p-Value T0 vs. T1 within each group was calculated with the Wilcoxon Signed ranks test.
**Between group comparisons of T1–T0 differences were tested with the Mann–Whitney U test.