Table 1.

Vasodilatory activities in Hojin formulations ((9), revised).

	Pharmacological action	Rokumigan	Hachimijiogan	Gosyajinkigan
Vascular endothelial cell	Nitric oxide synthesis	+	+	+
	Prostaglandin I2 synthesis	−	−	−
Vascular smooth muscle cell	Calcium channel inhibitor	+	+	+
	Protein kinase C inhibitor	+	+	+
	Beta receptor agonist	−	+	+