Table 3.
Personal history of Suicide Attempt vs. no history of suicide attempt, single marker analyses were established with standard chi-squared testing.
| CRHR1 | Power analysis | Genotypes | Alleles | HWE | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| SNP ID | N° of patients with suicide attempts | N° of patients without suicide attempts | Effect size (w) | Power (1–ß-error) | χ2 | p | χ2 | p | Patients with suicide attempts (p-value) | Patients without suicide attempts (p-value) |
| rs7209436 | 69 (CC: 26, TC: 29, TT: 14) | 181 (CC: 60, TC: 85, TT: 36) | 0.048 | 0.10 | 0.57 | 0.75 | 0.16 | 0.69 | 0.27 | 0.55 |
| rs4792887 | 70 (CC: 58, CT: 9, TT: 3) | 181 (CC: 146, CT: 34, TT: 1) | 0.140 | 0.49 | 4.89* | 0.07* | 0.06 | 0.80 | 0.024* | 1.00* |
| rs110402 | 70 (GG: 26, AG: 29, AA: 15) | 181 (GG: 56, AG: 83, AA: 42) | 0.060 | 0.12 | 0.89 | 0.64 | 0.59 | 0.44 | 0.21 | 0.30 |
| rs242924 | 70 (GG: 24, TG: 32, TT: 14) | 181 (GG: 55, TG: 83, TT: 43) | 0.047 | 0.10 | 0.56 | 0.76 | 0.55 | 0.46 | 0.58 | 0.29 |
| rs242939 | 70 (TT: 62, CT: 6, CC: 2) | 181 (TT: 154, CT: 26, CC: 1) | 0.119 | 0.37 | 3.51* | 0.12 | 0.05 | 0.83 | 0.03* | 1.00* |
CRHR1, Corticotropin Releasing Hormone Receptor 1; SNP, Single Nucleotide Polymorphism; N°, Number; HWE, Hardy–Weinberg-Equilibrium.
*
calculated with Fisher's Exact Test. Bold indicates a significant (>0.05) p-value.