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. 2018 Apr 30;6:e4683. doi: 10.7717/peerj.4683

Table 2. Delay of Aβ-induced paralysis in C. elegans strain CL4176.

PT50 are median values describing the point in time, when exactly 50% of the worms are paralysed. Experiments were conducted in different test series with slightly differing values of the control; p values compared to the respective control.

Series of experiments Treatment Concentration [µg/mL] PT50 ± S.E.M. [h] Significance
Set 1 Control (0.5% ethanol) 33.5 ± 0.5
Set 1 EGCG 100 35.5 ± 0.5 p < 0.05
Set 1 H2O 600 35.5 ± 0.5 p < 0.05
Set 1 EtOH20 600 35.0 ± 0.6 p < 0.05
800 35.5 ± 0.5 p < 0.05
1,000 35.8 ± 0.6 p < 0.05
Set 1 EtOH50 200 35.0 ± 0.6
400 35.5 ± 0.5 p < 0.05
600 37.0 ± 0.0 p < 0.001
Set 1 EtOH70 600 36.3 ± 0.3 p < 0.01
Set 2 Control (0.5% ethanol) 34.8 ± 0.3
Set 2 EGCG 100 35.8 ± 0.3 p < 0.05
Set 2 EtOH40 400 35.5 ± 0.3
600 36.5 ± 0.3 p < 0.01
Set 2 Liq-Liq BuOH 400 37.0 ± 0.6 p < 0.05
Set 2 Liq-Liq H2O 400 35.3 ± 0.3
Set 2 Reprecip. supernat. 400 36.8 ± 0.3 p < 0.01
Set 2 Reprecip. precip. 400 35.5 ± 0.3
Set 2 Resin EtOH 400 37.0 ± 0.4 p < 0.01
Set 2 Resin H2O 400 35.3 ± 0.3