Table 2. Delay of Aβ-induced paralysis in C. elegans strain CL4176.
PT50 are median values describing the point in time, when exactly 50% of the worms are paralysed. Experiments were conducted in different test series with slightly differing values of the control; p values compared to the respective control.
| Series of experiments | Treatment | Concentration [µg/mL] | PT50 ± S.E.M. [h] | Significance |
|---|---|---|---|---|
| Set 1 | Control (0.5% ethanol) | 33.5 ± 0.5 | ||
| Set 1 | EGCG | 100 | 35.5 ± 0.5 | p < 0.05 |
| Set 1 | H2O | 600 | 35.5 ± 0.5 | p < 0.05 |
| Set 1 | EtOH20 | 600 | 35.0 ± 0.6 | p < 0.05 |
| 800 | 35.5 ± 0.5 | p < 0.05 | ||
| 1,000 | 35.8 ± 0.6 | p < 0.05 | ||
| Set 1 | EtOH50 | 200 | 35.0 ± 0.6 | |
| 400 | 35.5 ± 0.5 | p < 0.05 | ||
| 600 | 37.0 ± 0.0 | p < 0.001 | ||
| Set 1 | EtOH70 | 600 | 36.3 ± 0.3 | p < 0.01 |
| Set 2 | Control (0.5% ethanol) | 34.8 ± 0.3 | ||
| Set 2 | EGCG | 100 | 35.8 ± 0.3 | p < 0.05 |
| Set 2 | EtOH40 | 400 | 35.5 ± 0.3 | |
| 600 | 36.5 ± 0.3 | p < 0.01 | ||
| Set 2 | Liq-Liq BuOH | 400 | 37.0 ± 0.6 | p < 0.05 |
| Set 2 | Liq-Liq H2O | 400 | 35.3 ± 0.3 | |
| Set 2 | Reprecip. supernat. | 400 | 36.8 ± 0.3 | p < 0.01 |
| Set 2 | Reprecip. precip. | 400 | 35.5 ± 0.3 | |
| Set 2 | Resin EtOH | 400 | 37.0 ± 0.4 | p < 0.01 |
| Set 2 | Resin H2O | 400 | 35.3 ± 0.3 |