Table 3.

In vitro susceptibilities of isavuconazole against medically important molds

Organism	MIC50 (mg/L)	MIC90 (mg/L)	References
Aspergillus fumigatus	0.25–1.0	0.5–2.0	36, 42, 45
Aspergillus terreus	0.38–0.5	0.5	42, 45
Aspergillus flavus	0.38–2.0	0.5–2.0	36, 42, 44, 45
Aspergillus niger	0.5	0.75–2.0	42, 45
Fusarium spp.	8.0–>32	>8.0–>32	44
Scedosporium	>32	>32	45
apiospermum
Mucor spp.	2	>32	44, 45
Rhizopus spp.	1	>32	44, 45

Abbreviations: MIC₅₀, minimum inhibitory concentration for 50% inhibitory; MIC₉₀, minimum inhibitory concentration for 90% inhibitory.