Table 2. Vision-Targeted HRQoL in Adult Retinoblastoma Survivors, Overall and by Laterality, as Reported on the NEI-VFQ-25.
| NEI-VFQ-25 | Mean (SD) | Difference Between Unilateral and Bilateral Survivors (95% CI) | P Value | |
|---|---|---|---|---|
| Unilateral Survivors (n = 218) |
Bilateral Survivors (n = 252) |
|||
| Overall VFQ score | 91.4 (7.7) | 72.3 (18.2) | 19.1 (16.5-21.7) | <.001 |
| Subscale score | ||||
| General health | 78.1 (20.4) | 69.0 (22.9) | 9.1 (5.2-13.2) | <.001 |
| General vision | 84.3 (14.4) | 46.1 (22.9) | 38.2 (33.0-43.4) | <.001 |
| Near vision | 94.5 (10.5) | 72.1 (25.6) | 22.4 (18.7-26.1) | <.001 |
| Distant vision | 94.3 (10.4) | 70.9 (25.2) | 23.3 (19.7-27.0) | <.001 |
| Driving | 89.6 (13.0) | 81.3 (19.8) | 8.3 (4.6-11.8) | <.001 |
| Peripheral vision | 80.1 (22.5) | 59.0 (32.8) | 21.1 (15.8-26.5) | <.001 |
| Color vision | 99.2 (5.1) | 87.0 (23.8) | 12.2 (8.9-15.1) | <.001 |
| Ocular pain | 90.3 (13.1) | 84.0 (19.5) | 6.3 (3.2-9.4) | .002 |
| Role difficulty | 91.1 (18.2) | 75.9 (25.8) | 15.2 (11.1-19.3) | <.001 |
| Dependency | 97.5 (9.3) | 81.6 (22.8) | 15.9 (12.7-19.2) | <.001 |
| Social functioning | 96.9 (8.7) | 80.0 (24.5) | 16.9 (13.2-20.2) | <.001 |
| Mental health | 88.2 (14.1) | 75.0 (23.1) | 13.2 (9.9-17.0) | <.001 |
Abbreviations: HRQoL, health-related quality of life; NEI-VFQ-25, 25-Item National Eye Institute Visual Function Questionnaire.