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. 2018 May;101(5):804–816. doi: 10.1016/j.pec.2017.10.015

Table 1.

Studies of psychoeducational interventions (PIs) for adolescents with depression, and families/carers.

Study, country Details of Intervention (and control) Study Design Participant characteristics (n) Assessment, follow-up Findings
Family PI
Sanford et al. [17], Canada Intervention: Randomised controlled trial 31 adolescents aged 13–18 years (20 females: 11 males), meeting DSM-IV criteria for MDD, and their families. Primary outcomes: Intervention improved RADS, SSAI, ACL post-treatment and follow-up, compared to usual treatment: effect size >0.5 for all.
Adjunctive PI: group sessions with all family members at home, PLUS usual treatment. (feasibility, effectiveness) (16:15) Reynolds Adolescent Depression Scale (RADS); Structured Social Adjustment Interview (SSAI) (adolescent social functioning); Family Assessment Device (FAD) (family functioning); Adjective Checklist (ACL) (adolescent-parent relationship) Effect size for RADS on follow-up: 0.64.
Twelve structured interactive 90-min sessions, with manual. Aims: increase family knowledge about depression, appreciate effects on family, improve communication between adolescent and family and coping strategies. Secondary outcomes: Greater satisfaction reported with intervention.
Control: Children’s Global Assessment Scale (CGAS) (adolescent); Client Satisfaction Questionnaire (CSQ) (parent satisfaction with services)
Usual treatment: individual/group counselling. Baseline (plus retest at 2 weeks), 3 months (mid-treatment), 6 months (post-treatment), 9 months (follow-up)
Lopez et al. [18], USA ‘Children’s Medication Algorithm Project (CMAP)’: Feasibility trial with 2 arms 90 children aged 6–17 years (26 females: 64 males) with diagnosis of depressive disorder, ADHD or both, being treated with medication in 4 community clinics. Parent Satisfaction Questionnaire; Child/Adolescent Satisfaction Questionnaire; CMAP Education Log Majority of caregivers (63%) and children (60%) happy with amount of information and found this helpful. 20% of parents and 14% of children/adolescents received much more information than they wanted. 90–100% of children and parents found written materials helpful.
Group intervention facilitated by clinicians/assistants, with manual, on medication, self-monitoring, lifestyle, coping strategies. Baseline, then 4-month intervals Programme successfully implemented, but follow-up data not analysed (confirmed from personal communication with authors).
Programme structured but could be tailored to families’ needs. Several available formats. No fixed number of sessions (median:6).
Aims: improve compliance with medication and coping strategies.
Brent et al. [19], USA 2-h session with manual, for parents on diagnosis, course, treatment, methods of coping with family member. Depression described as a chronic, recurrent illness. Trial of acceptability, feasibility, efficacy 62 parents of 34 adolescents (22 females: 12 males) with mood disorder (primarily depressive disorder). Questionnaire on attitude and knowledge about depression, and views of the programme
Baseline, post-intervention
Improvement in knowledge, modification of dysfunctional beliefs about depression and treatment.
‘Significant improvement’ on 8/21 questionnaire items, decline in one item.
Useful, interesting for almost all (97%) participants.



INDIVIDUAL PI
Parker et al. [20], Australia Simple low-intensity interventions. Factorial (2 × 2) randomised controlled trial 176 help-seeking 15–25 year olds (mean age 17.6 years) with sub-threshold or mild-moderate depression/anxiety. Primary outcomes: Reduction in depression symptoms in BAPA and PI groups, greater reduction with BAPA, but not anxiety symptoms. Effect size post-intervention: BDI-II: d = 0.41 (95% CI 0.07–0.76); MADRS: d = 0.48 (95% CI 0.13–0.82).
Up to 6 manualised weekly sessions. (acceptability, effectiveness) Lifestyle PI:86 (53 females:33 males), BAPA:88 (53 females:35 males) Beck Depression Inventory-II (BDI-II); Montgomery-Asberg Depression Rating Scales (MADRS); Beck Anxiety Inventory (BAI) Lifestyle PI:
Exercise: Behavioural activation physical activity (BAPA) v Lifestyle psychoeducation (e.g. physical activity, sleep, substance use) Secondary outcomes: BDI-II (mean): Baseline: 22.23, Post-intervention 14.09;
Psychological: Problem Solving Therapy v Supportive Counselling. Clinical caseness; Substance (use) and Choices Scale; Social and Occupational Functional Scale; Active Australia (physical activity) Survey; Questionnaire on other interventions received MADRS (mean): Baseline: 20.44, Post-intervention 12.87;
Baseline, post-intervention BAI (mean): Baseline: 15.56, Post-intervention 7.88.
Problem solving therapy not superior to supportive counselling. No interactions between interventions.



COMPUTERISED/ONLINE PI
Stasiak et al.[21], New Zealand Intervention: Randomised controlled trial 34 adolescents (13–18 years) with low mood (14 females: 20 males), self-referred to school counsellors across 8 urban schools. Primary outcome: Child Depression Rating Scale Revised (CDRS-R); Reductions in depression scores in both groups, greater reduction with cCBT.
‘The Journey’, computerised CBT programme (cCBT) at school, with guidebook. No school counsellor support unless requested. (feasibility, acceptability, effectiveness). (17:17) Secondary outcomes: RADS-2; Pediatric Quality of Life Inventory (PedsQL); Adolescent Coping Scale (ACS) CDRS-R mean change:
7 × 25–30 min multimedia modules (‘fantasy game-like environment’), on problem solving, conflict resolution, identifying and challenging unhelpful thoughts, relaxation techniques. Acceptability: Brief satisfaction questionnaire cCBT = 17.6 (CI = 14.13–21.00); CPE = 6.1 (CI = 2.01-10.02); p < 0.001. Effect size between groups: 1.7.
Control: Baseline, post-intervention, 1-month follow-up CPE had been helpful, positive feedback on computer-based format. Some felt it was more suited to younger ages.
Psychoeducation computer programme (CPE). Same structure as above but different content − on depression, ‘mental health hygiene’, stress reduction. CPE more ‘instructional’ than ‘therapeutic’.
Demaso et al. [22], USA ‘Depression Experience Journal (EJ)’: website for children/adolescents, families and healthcare professionals to share personal experiences of living/working with mental illness (to ‘facilitate healthy coping’). Used individually or with others. Development trial − feasibility, safety 38 primary caregivers, each with a child aged 8–19 years (26 females: 12 males) with depression, during a psychiatric hospital admission. 2 semi-structured interviews: Parents satisfied overall with EJ and presentation of stories and facts. Personal stories most helpful.
First assessed families’ experiences of child’s depression and management; They suggested greater number and wider variety of narratives, and more interactivity.
Second on views of intervention: using satisfaction & safety, concerns/areas for improvement, specific impacts, coping response & attitude change scales.
Baseline, 2–4 weeks after use
Stjernswärd & Hansson [23], Sweden Web-based support for relatives of individuals with depression − psychoeducation module, diary, forum. Explorative open trial 25 relatives of individuals (including adolescents) with depression. System usability scale (questionnaire);
Content analysis of forum
Generally well-received.
Intervention could help e.g. with feelings of isolation.