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Immune related adverse events (%) in patients treated with nivolumab.
| Study | CHECKMATE 063 [Horn et al. 2015] | ONO-4538-050 [Nakagawa et al. 2015] | CHECKMATE 017 [Brahmer et al. 2015] | |||
|---|---|---|---|---|---|---|
| Immune related adverse events | All grade | Grade 3/4 | Grade 3/4 | Grade 3/4 | All grade | Grade 3/4 |
| Skin | 15.5 | 0 | 0 | 0 | 28.6 | 0 |
| Gastrointestinal | 11.6 | 0.8 | 1 | 1 | 5.7 | 0 |
| Pulmonary | 7.0 | 2.3 | 1 | 1 | 5.7 | 0 |
| Endocrinopathies | 6.2 | 0 | 0 | 0 | 11.4 | 0 |
| Hepatitis | 4.7 | 0.8 | 0 | 0 | 5.7 | 0 |
| Renal injury | 3.1 | 0 | 1 | 1 | 2.9 | 0 |
