Table 4.
Summary of sensitivity analyses.
| Scenario | Description | Budget impact per patient (US$) | Change versus base case (absolute/%) | Reference |
|---|---|---|---|---|
| Base case | See Table 2 | −7886 | ||
| 1. Efficacy | NAVA: 0% | −8160 | 274/3% | Terzi et al. [2010] |
| PSV: 32% | ||||
| 2. Efficacy | NAVA: 0% | 9257 | 1371/17% | Colomboet al. [2008] |
| PSV: 36% | ||||
| 3. Efficacy | NAVA: 0% | −11,451 | 3565/45% | De la Olivaet al. [2012] |
| PSV: 44% | ||||
| 4. Efficacy | NAVA: 9% | −15,427 | 7541/96% | Moerer et al. [2008] |
| PSV: 67.5% | ||||
| 5. Efficacy | NAVA: 7% | −18,855 | 10,969/139% | Spahija et al. [2010] |
| PSV: 78% | ||||
| 6. Efficacy | NAVA: 0% | −19,952 | 12,066/153% | Cammarotaet al. [2011] |
| PSV: 75% | ||||
| 7. Catheter cost | US$700 | −7271 | −615/–8% | |
| 8. Catheter cost | US$1050 | −6656 | −1230/–16% | |
| 9. Catheter cost | US$1400 | −6041 | −1845/–23% | |
| 10. Frequency of catheter switch | Every third day | −7593 | −239/–4% | |
| 11. Frequency of catheter switch | Every day | −6329 | −1557/–20% | |
| 12. Daily ICU cost min, Sweden | NU Trollhättan: US$2461 | −3563 | −4323/–55% | Swedish ICU register |
| 13. Daily ICU cost median, Sweden | Kristianstad/Gävle: US$4370 | −6805 | −1081/–14% | Swedish ICU register |
| 14. Daily ICU cost max, Sweden | K Solna CIVA: US$5516 | −8750 | 864/11% | Swedish ICU register |
| 15. Days on MV | 3.7 days | −4579 | −3307/–42% | Swedish ICU register |
| 16. Days on MV | 1.45 days | −1532 | −6354/–81% | Hypothetical |
ICU, intensive care unit; MV, mechanical ventilation; NAVA, Neurally Adjusted Ventilator Assist; PSV, pressure support ventilation.