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. 2018 May 3;13(5):e0196761. doi: 10.1371/journal.pone.0196761

Table 2. In vitro growth inhibition of cancer cell lines by KuWal151 (8c)a.

Cell line Cancer origin GI50 [μM] SPF45b [FPKM]c CLK1 [FPKM]c
786–0 Renal Cancer 0.275 18 13
A498 Renal Cancer 0.166 10 9
A549/ATCC Non-Small Cell Lung Cancer 0.389 16 11
ACHN Renal Cancer 0.372 15 6
BT-549 Breast Cancer 0.204 n.a. n.a.
CCRF-CEM Leukemia 0.178 n.a. n.a.
COLO 205 Colon Cancer 0.209 n.a. n.a.
DU-145 Prostate Cancer 0.316 22 7
EKVX Non-Small Cell Lung Cancer 0.355 19 12
HCC-2998 Colon Cancer 0.912 n.a n.a
HCT-116 Colon Cancer 0.191 22 9
HCT-15 Colon Cancer 0.178 25 15
HL-60(TB) Leukemia 0.141 9 14
HOP-92 Non-Small Cell Lung Cancer 5.62 19 7
HS 578T Breast Cancer 0.204 6 8
HT29 Colon Cancer 0.174 19 15
IGROV1 Ovarian Cancer 0.427 21 11
K-562 Leukemia 0.162 18 9
KM12 Colon Cancer 0.209 20 39
LOX IMVI Melanoma 0.245 17 17
M14 Melanoma 0.132 n.a n.a
MCF7 Breast Cancer 0.174 19 11
MDA-MB-231/ATCC Breast Cancer 1.38 18 14
MDA-MB-435 Melanoma 0.0724 11 22
MDA-MB-468 Breast Cancer 0.234 20 11
MOLT-4 Leukemia 0.257 n.a n.a
NCI/ADR-RES Ovarian Cancer 0.178 n.a n.a
NCI-H226 Non-Small Cell Lung Cancer 28.8 8 6
NCI-H23 Non-Small Cell Lung Cancer 0.525 25 12
NCI-H322M Non-Small Cell Lung Cancer 2.39 7 13
NCI-H460 Non-Small Cell Lung Cancer 0.209 15 4
NCI-H522 Non-Small Cell Lung Cancer 0.158 9 15
OVCAR-3 Ovarian Cancer 0.191 12 11
OVCAR-4 Ovarian Cancer 0.912 15 9
OVCAR-5 Ovarian Cancer 1.25 n.a n.a
OVCAR-8 Ovarian Cancer 0.724 36 10
PC-3 Prostate Cancer 0.339 12 15
RPMI-8226 Leukemia 0.288 19 10
RXF 393 Renal Cancer 0.457 n.a n.a
SF-268 CNS Cancer 0.437 12 5
SF-295 CNS Cancer 0.224 11 8
SF-539 CNS Cancer 0.166 12 12
SK-MEL-2 Melanoma 0.316 n.a n.a
SK-MEL-28 Melanoma 0.692 8 12
SK-MEL-5 Melanoma 0.407 9 9
SK-OV-3 Ovarian Cancer 0.275 20 9
SN12C Renal Cancer 0.331 n.a n.a
SNB-19 CNS Cancer 0.389 n.a n.a
SNB-75 CNS Cancer 0.151 10 11
SR Leukemia 0.151 n.a n.a
SW-620 Colon Cancer 0.209 22 17
T-47D Breast Cancer 0.309 20 7
TK-10 Renal Cancer 10.2 n.a n.a
U251 CNS Cancer 0.263 n.a n.a
UACC-257 Melanoma >50.1 8 12
UACC-62 Melanoma 0.275 10 12
UO-31 Renal Cancer 0.832 10 6

a n.a. = not available

b synonym in Expression Atlas: RBM17

c FPKM (fragments per kilobase of exon model per million reads mapped) is a common unit of gene expression calculated from RNA-sequencing data. The calculation takes into account gene length and total number of mapped reads [46].