Table 3. Final multivariable models, following backward elimination of non-significant (P >0.05) variables, for which the outcome variables were the proportion of cases showing erythema migrans, neurological manifestations and cardiac manifestations.

Variable	Odds ratio	95% Confidence interval	Wald z	P value
Outcome = erythema migrans
Year 2010 versus 2009	1.364	0.616-3.018	0.77	>0.1
Year 2011 versus 2009	2.232	1.109-4.489	2.25	<0.05
Year 2012 versus 2009	2.860	1.416-5.778	2.93	<0.01
Age	1.015	1.004-1.027	2.71	<0.01
Outcome = neurological manifestations
Women versus men	0.561	0.345-0.940	-2.19	<0.05
Age	1.073	1.014-1.146	2.45	<0.05
Age squared	0.998	0.998-0.999	-0.30	<0.01
Ontario versus New Brunswick and Nova Scotia	3.781	1.849-7.772	3.62	<0.001
Outcome = cardiac manifestations
Age	1.305	1.043-1.632	2.33	<0.05
Age squared	0.997	0.994-0.999	-2.41	<0.05