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. 2018 Feb 21;26(3):274–281. doi: 10.4062/biomolther.2017.189

Table 3.

Donepezil pharmacokinetic parameters after oral treatment to hairless rats (mean ± SD)

Parameter PO (5 mg/head ≅ 17.9 mg/kg)
Tmax (h) 2.5 ± 0.5
Cmax (ng/ml) 97.3 ± 24.4
AUC0→inf (ng×h/ml) 1342.6 ± 115.5