Table 2.

A Cox regression analysis of the associations between 365 day mortality, cumulative heart failure events

	365 day mortality						Heart failure event
	Univariate analysis			Multivariate analysis			Univariate analysis			Multivariate analysis
	HR	95% CI	P value	HR	95% CI	P value	HR	95% CI	P value	HR	95% CI	P value
Anaemia status on Day 3
No‐AKI/no‐WRF	1.000			1.000			1.000			1.000
No‐AKI/WRF	1.395	0.895−2.174	0.141	1.248	0.768–2.028	0.370	1.210	0.896–1.635	0.214	1.110	0.803–1.534	0.527
AKI/no‐WRF	2.234	1.482–3.368	<0.001	1.916	1.234–2.974	0.004	1.214	0.883–1.667	0.232	1.060	0.748–1.502	0.742
AKI/WRF	5.942	4.025–8.771	<0.001	3.622	2.332–5.624	<0.001	3.288	2.431–4.446	<0.001	2.424	1.718–3.419	<0.001
Adjusted factors (data of Day 1)
Age (per 1 year increase)	1.034	1.019–1.049	<0.001	1.030	1.013–1.047	<0.001	1.026	1.015–1.036	<0.001	1.023	1.011–1.035	<0.001
SBP (per 10 mmHg increase)	0.857	0.827–0.889	<0.001	0.889	0.852–0.928	<0.001	0.931	0.906–0.957	<0.001	0.960	0.930–0.992	0.014
LVEF (per 1% increase)	0.999	0.991–1.008	0.895				0.993	0.987–1.000	0.063	0.989	0.981–0.996	0.003
Sodium (per 1.0 mmol/L increase)	0.937	0.913–0.961	<0.001				0.953	0.933–0.973	<0.001	0.974	0.952–0.997	0.030
Haemoglobin (per 1.0 mg/dL increase)	0.843	0.797–0.891	<0.001	0.934	0.874–0.999	0.046	0.892	0.855–0.930	<0.001	0.936	0.888–0.986	0.012
BNP (per 10 pg/mL increase)	1.002	1.002–1.003	<0.001	1.001	1.001–1.002	0.001	1.002	1.001–1.002	<0.001

AKI; acute kidney injury; BNP, brain natriuretic peptide; CI, confidence interval; HR, hazard ratio; LVEF, left ventricular ejection fraction measured on echocardiography; SBP, systolic blood pressure; WRF; worsening renal function.