Table 1. Baseline characteristics of patients with esophageal cancer receiving neoadjuvant chemoradiation.
| Characteristic | Advanced radiation n=1,740; (%) | 3D conformal n=1,398; (%) | P value |
|---|---|---|---|
| Age | |||
| <60 | 617 (35.5) | 559 (40.0) | 0.018 |
| 60–70 | 788 (45.3) | 608 (43.5) | |
| >70 | 335 (19.3) | 231 (16.5) | |
| Sex | |||
| Male | 1,451 (83.4) | 1,188 (85.0) | 0.227 |
| Female | 289 (16.6) | 210 (15.0) | |
| Race | |||
| White | 1,593 (91.6) | 1,295 (92.6) | 0.688 |
| African American | 66 (3.8) | 43 (3.1) | |
| Hispanic | 39 (2.2) | 29 (2.1) | |
| Other/not recorded | 42 (2.4) | 31 (2.2) | |
| Histology | |||
| Adenocarcinoma | 1,387 (79.7) | 1,185 (84.8) | <0.0001 |
| Squamous cell | 353 (20.3) | 213 (15.2) | |
| cT stage | |||
| T1b | 28 (1.6) | 10 (0.7) | <0.0001 |
| T2 | 293 (16.8) | 327 (23.4) | |
| T3 | 1,291 (74.2) | 1,057 (75.6) | |
| T4a | 29 (1.7) | 4 (0.3) | |
| pN stage | |||
| N0 | 589 (33.9) | 519 (37.1) | <0.0001 |
| N1 | 949 (54.5) | 785 (56.2) | |
| N2–3 | 202 (11.6) | 94 (6.7) | |
| Charlson Deyo score | |||
| 0 | 1,299 (74.7) | 1,063 (76.0) | 0.455 |
| 1 | 355 (20.4) | 278 (19.9) | |
| 2 | 86 (4.9) | 57 (4.1) | |
| Tumor location | |||
| Cervical/upper | 25 (1.4) | 13 (0.9) | 0.159 |
| Thoracic/middle | 202 (11.6) | 134 (9.6) | |
| Abdominal/lower | 1,377 (79.1) | 1,136 (81.3) | |
| Overlapping | 81 (4.7) | 60 (4.3) | |
| Not recorded | 55 (3.2) | 55 (3.9) | |
| Facility type | |||
| Non academic | 804 (46.2) | 801 (57.3) | <0.0001 |
| Academic | 907 (52.1) | 573 (41.0) | |
| Not recorded | 29 (1.7) | 24 (1.7) | |
| Insurance | |||
| Medicaid | 87 (5.0) | 77 (5.5) | 0.246 |
| Private | 869 (49.9) | 721 (51.6) | |
| Medicare | 693 (39.8) | 542 (38.8) | |
| Not insured | 41 (2.4) | 34 (2.4) | |
| Other/not recorded | 50 (2.9) | 24 (1.7) | |
| Income | |||
| <$46,000 | 972 (55.9) | 778 (55.7) | 0.044 |
| $46,000+ | 705 (40.5) | 590 (42.2) | |
| Not recorded | 63 (3.6) | 30 (2.1) | |
| Year of diagnosis | |||
| 2004–2008 | 215 (12.4) | 462 (33.0) | <0.0001 |
| 2009–2013 | 1,525 (87.6) | 936 (67.0) | |
| Distance from facility | |||
| ≤20 miles | 1,022 (58.7) | 841 (60.2) | 0.455 |
| >20 miles | 703 (40.4) | 550 (39.3) | |
| Not recorded | 14 (0.8) | 7 (0.5) | |
| Region | |||
| Northeast | 432 (24.8) | 325 (23.2) | <0.0001 |
| Southeast | 471 (27.1) | 330 (23.6) | |
| Southwest | 69 (4.0) | 15 (1.1) | |
| Midwest | 483 (27.8) | 534 (38.2) | |
| West | 256 (14.7) | 169 (12.1) | |
| Not recorded | 29 (1.7) | 25 (1.8) | |
| Post-operative statistics | |||
| 30-day mortality | 65 (3.74) | 47 (3.4) | 0.575 |
| 90-day mortality | 135 (7.8) | 95 (6.8) | 0.303 |
| Length of postoperative hospital stay | 12.2 days | 12.2 days | 0.955 |
| 30-day readmission | 104 (6.0) | 83 (5.9) | 0.963 |