Table 2.
Results of univariate regression analysis of hepatic and muscle insulin sensitivity using data of 29 non‐obese type 2 diabetes patients
% Reduction of EGP | Rd | |||
---|---|---|---|---|
r | P‐value | r | P‐value | |
Age | 0.33 | 0.08 | −0.002 | 0.99 |
Duration | 0.06 | 0.75 | 0.003 | 0.99 |
BMI | −0.29 | 0.13 | −0.36 | 0.06 |
Total body fat content | −0.10 | 0.60 | −0.44a | <0.05a |
Systolic blood pressure | 0.08 | 0.68 | 0.16 | 0.40 |
Diastolic blood pressure | −0.02 | 0.94 | 0.03 | 0.90 |
Waist | −0.16 | 0.42 | −0.01 | 0.62 |
Alcohol intake | −0.07 | 0.74 | 0.06 | 0.77 |
Aspartate aminotransferase | −0.31 | 0.10 | −0.30 | 0.12 |
Alanine aminotransferase | −0.58a | <0.01a | −0.67a | <0.01a |
γ‐Glutamyl transferase | −0.41a | <0.05a | −0.33 | 0.09 |
Platelet | −0.04 | 0.84 | −0.02 | 0.93 |
Type 4 collagen | −0.19 | 0.33 | 0.20 | 0.29 |
Ferritin | −0.43a | <0.05a | −0.34 | 0.07 |
Fasting plasma glucose | −0.37 | 0.05 | −0.36 | 0.06 |
Fasting serum insulin | −0.22 | 0.25 | −0.64a | <0.01a |
HbA1c | −0.21 | 0.28 | −0.35 | 0.06 |
HOMA‐IR | −0.40a | <0.05a | −0.67a | <0.01a |
LDL cholesterol | 0.12 | 0.53 | −0.18 | 0.35 |
HDL cholesterol | −0.01 | 0.94 | 0.25 | 0.19 |
Triglyceride | −0.30 | 0.11 | −0.27 | 0.15 |
Basal EGP | 0.02 | 0.91 | 0.24 | 0.22 |
Free fatty acid | 0.16 | 0.42 | −0.20 | 0.31 |
HMW‐adiponectin | 0.26 | 0.18 | 0.30 | 0.12 |
CRP | −0.33 | 0.08 | −0.08 | 0.68 |
Visceral fat area | −0.13 | 0.51 | −0.23 | 0.23 |
Subcutaneous fat area | −0.08 | 0.68 | −0.16 | 0.41 |
Intrahepatic lipid | −0.02 | 0.92 | −0.32 | 0.09 |
IMCL in tibialis anterior muscle | 0.01 | 0.95 | 0.11 | 0.60 |
Statistically significant.
BMI, body mass index; CRP, C‐reactive protein; EGP, endogenous glucose production; HbA1c, glycated hemoglobin; HDL, high‐density lipoprotein; HOMA‐IR, homeostasis model assessment of insulin resistance; HMW, high molecular weight; IMCL, intramyocellular lipid; Rd, rate of glucose disposal.