Table 2.

Comparison of skin laser Doppler (SLD) variables between volunteers and patients and between survivors and non-survivors

SLD variable	Healthy volunteers and initial cohort			Initial cohort			Confirmatory cohort
	Volunteers (n = 18)	Patients (n = 29)	P	Survivors (n = 18)	Non-survivors (n = 11)	P	Survivors (n = 17)	Non-survivors (n = 18)	P
Skin blood flow 37 °C (PU)	10.3 (8.0–14.2)	13.0 (10.1–19.5)	0.16	13.4 (10.0–21.6)	13.0 (10.1–19.5)	0.44	12.4 (8.0–17.3)	15.0 (10.2–19.3)	0.44
Skin blood flow 43 °C (PU)	112.8 (88.0–150.0)	36.4 (25.6–76.9)	< 0.01	51.8 (25.6–77.2)	33.7 (16.5–39.0)	0.76	57.4 (41.5–71.5)	33.1 (21.8–41.6)	< 0.01
Skin blood flow ratio	11.2 (9.4–13.4)	2.6 (2.0–3.6)	< 0.01	3.2 (2.2–6.2)	2.3 (1.7–2.8)	< 0.01	3.7 (2.9–6.2)	2.1 (1.6–2.5)	< 0.01

PU perfusion units