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Effect of age and dietary restriction on the expression of genes involved in DNA methylation. The levels of the various transcripts were measured by qPCR for colon mucosa isolated from young (9 months, light blue) and old (24 months, dark blue) mice fed ad libitum and old (24 months, red) DR mice. Each bar represents the mean ± SEM of five mice per group. * P < 0.05; **P < 0.01; ***P < 0.001.
