Table 3. Prognostic factors for LC at irradiated sites.
Factor | n | 5-y LC | P value |
---|---|---|---|
Site of irradiated metastasis | |||
Bone | 166 | 79% | .65 |
Soft tissue | 78 | 85% | |
No. of bony sites of involvement at diagnosis | |||
≤5 | 102 | 83% | |
>5 | 141 | 80% | .84 |
Persistent disease in metastatic site after induction chemotherapy (bone and soft tissue) | |||
Yes | 107 | 67% | |
No | 137 | 92% | <.0001 |
Persistent bone disease after induction chemotherapy | |||
Yes | 88 | 66% | <.0001 |
No | 78 | 93% | |
Persistent soft tissue disease after induction chemotherapy | |||
Yes | 18 | 71% | .13 |
No | 60 | 91% | |
Site of bone involvement | |||
Skull and/or orbit | 76 | 86% | .36 |
Extremity | 59 | 70% | |
Pelvis | 10 | 77% | |
Spine | 18 | 81% | |
Other | 3 | 100% | |
RT dose | |||
<21 Gy | 15 | 88% | .02 |
21-24 Gy | 212 | 83% | |
30 Gy | 9 | 50% | |
36 Gy | 8 | 50% |
Abbreviations: LC = local control; RT = radiation therapy.