Figure 4.
Example patient showing measures generated by the surface-based morphometry approach in the parietal lobe. Note the multifocal appearance of each individual feature map. Information from each individual feature map was integrated by machine learning to generate a final cluster showing excellent concordance with expert labeling. Gray-white matter intensity measures blurring at the gray-white boundary; local cortical deformation (LCD) measures folding complexity; doughnut thickness measures local thickness variability; doughnut intensity measures local intensity variability at the gray-white boundary; interhemispheric gray-white matter intensity asymmetry measures the difference of bihemispheric blurring at the gray-white boundary; interhemispheric LCD asymmetry measures the difference of bihemispheric folding complexity; interhemispheric doughnut thickness measures the difference of bihemispheric local thickness variability; interhemispheric doughnut intensity measures the difference of bihemispheric local intensity variability at the gray-white boundary.
