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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Proteins. 2018 Mar 25;86(6):664–675. doi: 10.1002/prot.25493

Figure 2. Cladogram of ACPs Colored by Module Type.

Figure 2

An analysis of the ACPs from 33 trans-AT assembly lines and 10 ACPs from cis-AT assembly lines revealed that ACPs from the same types of modules clade together and helped to define the most common module types (Figure S1). Shown here is the cladogram of the ACPs from twenty-five module types (a–y), characterized by the moiety they add as well as the classes of enzyme they contain (KSs and KRs are divided into four clades as in Figures S2 & S3). ACP families (I–VIII) that contain related module types were also defined. Suspected gatekeeping enzymes are conservatively indicated with gate icons.