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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Proteins. 2018 Mar 25;86(6):664–675. doi: 10.1002/prot.25493

Figure 3. Cladograms of KSs Upstream and Downstream of ACPs Support the Updated Module Boundaries.

Figure 3

A) The lack of clustering for KSs upstream of ACPs that clade together, with the anticipated exception of KSs from the first module of bimodules, indicates ACPs do not usually evolutionarily co-migrate with the KS upstream of them. B) Clustering is observed for KSs downstream of ACPs that clade together. This observation suggests that ACPs evolutionarily generally co-migrate with the KS downstream of them, reaffirming the updated module boundaries. Colored dots indicate condensation-incompetent KS0s.