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. 2018 May 3;8:6954. doi: 10.1038/s41598-018-25295-x

Figure 4.

Figure 4

Autophagy is not decreased in kidneys of STZ-injected type-1 diabetic miR-192-KO mice compared to control mice. (A) Representative immunostaining and quantification for p62, Atg5 and glomerular area from cortical sections of 22-week old control and STZ-injected -WT and miR-192-KO mice; n = 5 per group. Scale bar, 20 µm. x400 (10 × 40) magnification. (B) Bar graphs showing quantification for p62, Atg5 and glomerular area. **P < 0.01; ***P < 0.001. (C) Representative immunostaining and quantification for pFoxO3a from cortical sections of 22-week old control and STZ-injected -WT and miR-192-KO mice; n = 5 per group. Scale bar, 20 µm. (D) Bar graphs showing quantification for pFoxO3a. ***P < 0.001.