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. 2018 Apr 27;9:451. doi: 10.3389/fphys.2018.00451

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Copyright © 2018 Zaninoni, Fermo, Vercellati, Consonni, Marcello, Zanella, Cortelezzi, Barcellini and Bianchi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Examples of typical osmoscan profiles in hemolytic anemias. Continuous line represents a daily control and shaded area the control range curve. (A) HS = hereditary spherocytosis: HS1 (), HS2 (); (B) HE = hereditary elliptocytosis: HE1 (), HE2 (); (C) HSt = hereditary stomatocytosis: HSt-PIEZO1 (), HSt-KCNN4 (); (D) CDAII (non-splenectomised) = congenital diserythropoietic anemia type II; (E) PKD (non-splenectomised) = pyruvate kinase deficiency; (F) GPI = glucosephosphate isomerase deficiency.

Inline graphic — Examples of typical osmoscan profiles in hemolytic anemias. Continuous line represents a daily control and shaded area the control range curve. (A) HS = hereditary spherocytosis: HS1 (), HS2 (); (B) HE = hereditary elliptocytosis: HE1 (), HE2 (); (C) HSt = hereditary stomatocytosis: HSt-PIEZO1 (), HSt-KCNN4 (); (D) CDAII (non-splenectomised) = congenital diserythropoietic anemia type II; (E) PKD (non-splenectomised) = pyruvate kinase deficiency; (F) GPI = glucosephosphate isomerase deficiency.