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. 2018 May 4;4(2):00124-2017. doi: 10.1183/23120541.00124-2017

TABLE 2.

Baseline right heart catheter and noninvasive variables

Total derivation cohort mPAP <25 mmHg mPAP 25–34 mmHg mPAP ≥35 mmHg p-value
Subjects 210 46 79 85  
Age years 61±11 63±11 64±11 58±12 0.004
Male % 55 52 54 56 0.9
ILD diagnosis    
 CTD 59 (28) 15 (25) 21 (36) 23 (39) 0.7
 Sarcoidosis 43 (20) 4 (9) 14 (33) 25 (58) 0.01
 IPF 62 (29) 18 (29) 28 (45) 16 (26) 0.02
 CHP 16 (8) 6 (38) 2 (12) 8 (50) 0.1
 NSIP 16 (8) 2 (12) 8 (50) 6 (38) 0.5
 Other ILD 14 (7) 1 (7) 6 (43) 7 (50) 0.4
Right heart catheter    
 mPAP mmHg 33±11 20±4 29±3 43±7 <0.001
 PVR Wood units 6.0±3.6 2.6±1.5 4.6±1.8 8.8±3.8 <0.001
 Cardiac output L·min−1·m−2 4.3±1.3 4.8±1.3 4.1±1.3 4.1±1.2 0.02
 PCWP mmHg 10±5 8±5 10±5 11±5 0.008
BNP ng·L−1 102 (44–266) 48 (30–72) 90 (42–141) 241 (105–436) <0.001
Pulmonary function tests    
 FEV1 L 1.6±0.6 1.6±0.6 1.5±0.5 1.6±0.6 0.9
 FEV1 % pred 58±18 62±21 57±17 57±17 0.2
 FVC L 2.0±0.8 2.0±0.8 1.9±0.7 2.2±0.9 0.2
 FVC % pred 60±20 61±22 59 ±18 62±22 0.7
 TLCO % pred 25±10 28±10 25±9 24 ±10 0.04
 KCO % pred 52±17 59±18 54±16 48±16 <0.001
 PaO2 kPa 7.9±1.9 8.9±1.9 8.1±1.9 7.1±1.7 <0.001
CT scan    
 ILD extent <20%/>20% 14/86 15/85 19/81 9/91 0.2

Data are presented as n, mean±sd, n (%) or median (interquartile range), unless otherwise stated. mPAP: mean pulmonary pressure at right heart catheterisation; ILD: interstitial lung disease; CTD: connective tissue disease; IPF idiopathic pulmonary fibrosis; CHP: chronic hypersensitivity pneumonitis; NSIP: nonspecific interstitial pneumonia; PVR: pulmonary vascular resistance; PCWP: pulmonary capillary wedge pressure; BNP: brain natriuretic peptide; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; TLCO: transfer factor of the lung for carbon monoxide; KCO: transfer coefficient of the lung for carbon monoxide; PaO2 : arterial oxygen tension (by capillary blood gas analysis); CT: computed tomography.