FIGURE 1.

Bβ_15-42 reduces inflammatory response and endothelial activation. To analyze the endothelial activation (A) and endothelial integrity (B) after IR injury, we performed RT-PCR analyses relative to 18S and western blot analyses relative to β-actin of relevant genes and proteins in kidney tissue homogenates (n = 8 per group for RT-PCR and western blot analyses). ^∗ Significant difference between Bβ_15-42 and saline treated mice at one point in time; x significant difference to CTRL; f significant difference in the time course within Bβ_15-42 treated or saline treated mice. ^x/f p < 0.05; ^xx/ff p < 0.01; ^{∗∗∗/xxx/fff} p < 0.001.