Table 2.
Prognostic factors for overall survival in hepatocellular carcinoma patients
| Clinicopathological features | Overall Survival | ||||
|---|---|---|---|---|---|
|
| |||||
| Univariate | Multivariate | ||||
|
| |||||
| Log-rank | P | HR | 95% CI | P value* | |
| Age | 0.013 | 0.909 | |||
| < 60 years | |||||
| ≥ 60 years | |||||
| Gender | 0.003 | 0.953 | |||
| Male | |||||
| Female | |||||
| Hepatitis B | 1.140 | 0.286 | |||
| Negative | |||||
| Positive | |||||
| Tumor size | 2.267 | 0.132 | |||
| < 5 cm | |||||
| ≥ 5 cm | |||||
| Tumor multiplicity | 4.383 | 0.036 | Not included | ||
| Single | |||||
| Multiple | |||||
| Histological differentiation | 4.183 | 0.041 | |||
| Moderate/Well | Reference | ||||
| Poor | 3.336 | 1.468-7.583 | 0.004 | ||
| α-fetoprotein level | 1.851 | 0.174 | |||
| < 20 ng/ml | |||||
| ≥ 20 ng/ml | |||||
| BCLC stage | 21.333 | < 0.001 | |||
| 0/A | Reference | ||||
| B | 33.333 | 7.463-142.857 | < 0.001 | ||
| miR-337-3p expression level | 4.844 | 0.028 | |||
| High | Reference | ||||
| Low | 6.926 | 1.883-25.473 | 0.004 | ||
*
P < 0.05 was considered to be statistically significance.