Figure 1.

ELISA measurement and flow cytometric analysis for determining circulating inflammatory levels at 24 h and 72 h after SS induction. A: Circulating level of tumor necrosis factor (TNF)-α at 24 h after SS induction, * vs. other groups with different symbols (†, ‡, §), P < 0.001. B: Circulating level of CD11^b/c+ cells, * vs. other groups with different symbols (†, ‡, §), P < 0.001. C: Circulating level of Ly6G+ cells, * vs. other groups with different symbols (†, ‡, §), P < 0.001. D: Circulating level of macrophage migration inhibitor factor (MIF)+ cells, * vs. other groups with different symbols (†, ‡, §), P < 0.001. All statistical analyses were performed by one-way ANOVA, followed by Bonferroni multiple comparison post hoc test (n = 6 for each group). Symbols (*, †, ‡, §) indicate significance at the 0.05 level. SC = sham control; SS = sepsis syndrome; AMSC^EXO = apoptotic adipose-derived mesenchymal stem cell-derived exosomes; HMSC^EXO = healthy adipose-derived mesenchymal stem cell-derived exosomes.