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. 2018 Apr 30;16(2):168–177. doi: 10.5217/ir.2018.16.2.168
Summary statement Average agreement score and rate of agreement
1. At the time of diagnosis, extensive small-intestinal lesions (EL2) and significant upper gastrointestinal tract disease (EL3) are predictive factors for complicated disease behavior in CD. 7.6 (85%)
2. Young age at diagnosis, need for steroids at first flare, and perianal disease at diagnosis predict a disabling course of CD (EL3). 8.0 (100%)
3. Smoking can predict the need for therapy intensification in CD (EL3), development of complicated disease behavior (EL3), and the need for surgery (EL3). 7.6 (95%)
4. Endoscopic severity of CD predicts the formation of fistulae (EL4) and the need for surgery (EL3). 8.3 (100%)