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. 2018 Apr 30;16(2):168–177. doi: 10.5217/ir.2018.16.2.168
Summary statement Average agreement score and rate of agreement
1. Surgery risk increases for people less than 40 years at the time of diagnosis (EL2). Surgery risk is lower if CD is diagnosed in early childhood (EL3) and in old age (EL2). 7.0 (75%)
2. Surgery risk is higher for small-intestinal lesions (in comparison with large-intestinal lesions) (EL2). 8.5 (100%)
3. Penetrating and stricturing phenotypes at diagnosis are independent risk factors for surgery compared to inflammatory type (EL2). 8.2 (90%)
4. Severe ulcers at colonoscopy in patients with colonic CD may predict need for surgery (EL4). 7.8 (95%)
5. Compared to inflammatory type, fistulizing and stricturing phenotypes are predictive factors for hospitalization and re-hospitalization (EL2). 8.5 (95%)
6. L4 lesions are a predictor of increased hospitalization and hence might be a more serious subgroup (EL3). By contrast, large-intestinal lesions predict a decrease in the hospitalization rate (EL2). 7.5 (86%)
7. Penetrating disease and younger age at diagnosis may predict increased risk of intestinal failure; bowel-sparing surgery and cases without stoma involvement may protect against intestinal failure (EL3). 7.7 (92%)
8. Complex perianal fistulae, anal-canal stricture, perineal lesions, large perianal abscesses, fecal incontinence, and distal bowel lesions are risk factors for permanent stoma (EL3). 8.3 (100%)