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. 2018 Mar 13;46(8):e45. doi: 10.1093/nar/gky053

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© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 6. — N-Myc (Mycn) as a potential driver of differential AFEs during iPSC reprogramming. (A) The gene set enrichment analysis (GSEA) like plot for N-Myc (Mycn). Differential AFEs were ranked based on the correlation of their PSI values to Mycn expression levels during the time course. Differential AFEs containing the Mycn motif were significantly enriched towards the top of the list. (B) The expression levels of Mycn across the time course. (C) The PSI values of Mycn-associated AFEs across the time course. The PSI value of each individual AFE is drawn in gray and the red curve represents the average of all AFEs.