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| Compound | CC50 (μM) |
|---|---|
| ciprofloxacin | 0.18 |
| t1 | 0.75 |
| t2 | 2.25 |
| t3 | 1.08 |
| b1 | 4.45 |
All these values were obtained with a single preparation of wild-type E. coli DNA gyrase. The CC50 value is defined as the concentration giving half the total amount of cleavage obtained at saturating amount of compound.
