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. 2018 Mar 15;15(5):7523–7530. doi: 10.3892/ol.2018.8266

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Copyright: © Ye et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Downregulation of AFAP1-AS1 inhibits GC cell migration and invasion ability. SGC-7901 and BGC-823 cells were used to detect the ability of migration and invasion. (A) Migration of cells into the scratched area was monitored at the indicated time points. Representative microscopic images (magnification, ×40) and the migration rates of each groups at 0 and 48 h are presented. (B) Representative microscopic images of invasive cells from the shNC and shAPAF1-AS1 groups (top panel; magnification, ×100). The relative number of invaded cells in each group was measured by determining the absorbance at 570 nm (bottom panel). Data were assessed by Student's t-test. *P<0.05. AFAP1-AS1, AFAP1-antisense RNA 1; GC, gastric cancer; sh, short hairpin; shNC, scrambled control shRNA.