Table 2.
Prediction of unfavorable outcome by multivariable modeling of baseline clinical characteristics
Coef. | Std.Err | |
---|---|---|
Not in remission a N = 156 | ||
β0=-1.58 | 0.44 | |
Cumulative active joint count | β1=0.04 | 0.05 |
ESR mm/h | β2=0.03 | 0.02 |
CRP >10 mg/L | β3=-0.07 | 0.69 |
Morning stiffness > 15 min | β4=1.16 | 0.45 |
Physician’s global assessment VAS | β5=0.16 | 0.46 |
ANA-positive | β6=1.25 | 0.50 |
HLA-B27-positive | β7=1.37 | 0.54 |
Ankle joint arthritis | β8=1.10 | 0.49 |
Functional disability (CHAQ), N = 141 | ||
β0=-1.68 | 0.35 | |
Cumulative active joint count | β1=-0.02 | 0.03 |
ESR mm/h | β2=0.01 | 0.01 |
CRP > 10 mg/L | β3=-0.20 | 0.63 |
Morning stiffness > 15 min | β4=1.03 | 0.42 |
Physician’s global assessment VAS | β5=-0.40 | 0.56 |
Finger joint arthritis | β6=1.21 | 0.54 |
Pain VAS | β7 = 0.77 | 0.40 |
Functional disability (PhS), N = 92 | ||
β0=-3.40 | 0.75 | |
Cumulative active joint count | β1=0.10 | 0.05 |
ESR mm/h | β2=0.01 | 0.02 |
CRP > 10 mg/L | β3=-2.06 | 1.28 |
Morning stiffness > 15 min | β4=1.68 | 0.80 |
Physician’s global assessment VAS | β5=-0.71 | 0.88 |
Pain VAS | β6=1.30 | 0.64 |
Joint damage (JADI-A), N = 141 | ||
β0=-3.84 | 0.76 | |
Cumulative active joint count | β1=0.02 | 0.04 |
ESR mm/h | β2=0.01 | 0.02 |
CRP > 10 mg/l | β3= -0.11 | 0.83 |
Morning stiffness > 15 min | β4=-0.59 | 0.61 |
Physician’s global assessment VAS | β5=0.28 | 0.52 |
Finger joint arthritis | β6=1.84 | 0.68 |
Older age at disease onset (years) | β7= 0.16 | 0.07 |
Coef. coefficients in the logistic regression, Std.Err. standard error in the coefficients, VAS visual analogue scale, ESR erythrocyte sedimentation rate for an increase in 10 mm/h, CRP C-reactive protein, ANA antinuclear antibody, HLA-B27 human leucocyte antigen
aNot in remission equals non-achievement of remission off medication