Table 2.

Dynamic change for serum inflammatory cytokines of NPE and CNSD children patients

Group	Cases	IL-6	TNF-α	IL-4	IL-10	IL-17	IFN-γ
Group NPE
1 day after admission	42	70.56 ± 17.20	58.19 ± 20.67	20.24 ± 5.13	64.11 ± 19.14	55.67 ± 42.18	56.61 ± 10.94
3 days after admission	42	74.80 ± 20.68	52.74 ± 20.22	22.83 ± 3.63	80.14 ± 19.20	53.33 ± 25.22	58.42 ± 9.17
5 days after admission	42	63.73 ± 23.85	30.08 ± 12.20	21.28 ± 4.50	59.92 ± 20.95	48.10 ± 27.22	55.31 ± 8.94
Group CNSD
1 day after admission	47	65.70 ± 18.27	54.57 ± 22.01	19.05 ± 5.78	59.56 ± 22.85	48.14 ± 33.26	48.91 ± 11.73
3 days after admission	47	55.99 ± 13.86	33.57 ± 11.43	20.38 ± 4.54	59.68 ± 16.98	44.81 ± 28.44	53.11 ± 8.96
5 days after admission	47	49.23 ± 13.34	28.92 ± 10.09	19.60 ± 4.54	42.12 ± 16.52	34.29 ± 27.33	45.88 ± 11.06
Value i  Finterblock value (P value)		7.855 (0.077)	3.644 (0.042)	4.361 (0.052)	16.823 (0.000)	3.061 (0.084)	20.142 (0.000)
Ftime value (P value)		1.876 (0.177)	13.133 (0.001)	0.873 (0.354)	14.580 (0.001)	1.329 (0.254)	3.093 (0.045)
Finteraction value (P value)		2.192 (0.145)	0.2919 (0.592)	0.152 (0.618)	2.612 (0.078)	3.736 (0.059)	0.513 (0.600)

CNSD, central nervous system disease; NPE, neurogenic pulmonary edema; F_interblock value, It refers to the variation (F value) between NPE group and CNSD group; F_time value, it refers to the variation of different time (1, 3, 5 days) about NPE group or CNSD group; F_interaction value, it refers to the interaction variation of group and time. ANOVA of repeated measurement data was used for the statistical test about the comparisons made between or intra-groups