Table 3.
Positivity of HPV infection in study participants in northeastern Guangdong Province of China
| HPV type | 2013(N = 10,081) | 2014(N = 12,876) | 2015(N = 5773) | P | |||
|---|---|---|---|---|---|---|---|
| n | %(95%CI) | n | %(95%CI) | n | %(95%CI) | ||
| 6 | 38 | 0.38 (0.26–0.50) | 57 | 0.44 (0.33–0.56) | 54 | 0.94 (0.69–1.18) | < 0.001 |
| 11 | 45 | 0.45 (0.32–0.58) | 65 | 0.50 (0.38–0.63) | 38 | 0.66 (0.45–0.87) | 0.085 |
| 16 | 401 | 3.98 (3.60–4.36) | 626 | 4.86 (4.49–5.23) | 404 | 7.00 (6.34–7.66) | < 0.001 |
| 18 | 91 | 0.90 (0.72–1.09) | 136 | 1.06 (0.88–1.23) | 113 | 1.96 (1.60–2.31) | < 0.001 |
| 31 | 54 | 0.54 (0.39–0.68) | 93 | 0.72 (0.58–0.87) | 80 | 1.39 (1.08–1.69) | < 0.001 |
| 33 | 94 | 0.93 (0.74–1.12) | 132 | 1.03 (0.85–1.20) | 89 | 1.54 (1.22–1.86) | 0.001 |
| 35 | 6 | 0.06 (0.01–0.11) | 13 | 0.10 (0.05–0.16) | 20 | 0.35 (0.16–0.50) | < 0.001 |
| 39 | 41 | 0.41 (0.28–0.53) | 115 | 0.89 (0.73–1.06) | 69 | 1.20 (0.91–1.48) | < 0.001 |
| 42 | 4 | 0.04 (0.00–0.08) | 7 | 0.05 (0.01–0.09) | 18 | 0.31 (0.17–0.46) | < 0.001 |
| 43 | 0 | 0.00 | 3 | 0.02 (0.00–0.05) | 7 | 0.12 (0.03–0.21) | < 0.001 |
| 44 | 15 | 0.15 (0.07–0.22) | 32 | 0.25 (0.16–0.33) | 29 | 0.50 (0.32–0.68) | < 0.001 |
| 45 | 22 | 0.22 (0.13–0.31) | 25 | 0.19 (0.12–0.27) | 10 | 0.17 (0.07–0.28) | 0.529 |
| 51 | 10 | 0.10 (0.04–0.16) | 104 | 0.81 (0.65–0.96) | 131 | 2.27 (1.89–2.65) | < 0.001 |
| 52 | 254 | 2.52 (2.21–2.83) | 388 | 3.01 (2.72–3.31) | 248 | 4.30 (3.77–4.82) | < 0.001 |
| 53 | 99 | 0.98 (0.79–1.17) | 165 | 1.28 (1.09–1.48) | 103 | 1.78 (1.44–2.13) | < 0.001 |
| 56 | 14 | 0.14 (0.07–0.21) | 42 | 0.33 (0.23–0.42) | 27 | 0.47 (0.29–0.64) | < 0.001 |
| 58 | 214 | 2.12 (1.84–2.40) | 359 | 2.79 (2.50–3.07) | 200 | 3.46 (2.99–3.94) | < 0.001 |
| 59 | 18 | 0.18 (0.10–0.26) | 29 | 0.23 (0.14–0.31) | 18 | 0.31 (0.17–0.46) | 0.096 |
| 66 | 31 | 0.31 (0.20–0.42) | 54 | 0.42 (0.31–0.53) | 59 | 1.02 (0.76–1.28) | < 0.001 |
| 68 | 89 | 0.88 (0.70–1.07) | 87 | 0.68 (0.53–0.82) | 39 | 0.68 (0.46–0.89) | 0.095 |
| cp8304 | 76 | 0.75 (0.59–0.92) | 117 | 0.91 (0.74–1.07) | 103 | 1.78 (1.44–2.12) | < 0.001 |
| 6/11 | 83 | 0.82 (0.65–1.00) | 120 | 0.93 (0.77–1.10) | 89 | 1.54 (1.22–1.86) | < 0.001 |
| 16/18 | 484 | 4.80 (4.38–5.22) | 755 | 5.86 (5.46–6.27) | 510 | 8.83 (8.10–9.57) | < 0.001 |
| 4vHPV | 567 | 5.625.17–6.07) | 875 | 6.80 (6.36–7.23) | 599 | 10.38 (9.59–11.16) | < 0.001 |
| 9vHPV | 1123 | 11.14 (10.53–11.75) | 1706 | 13.25 (12.66–13.84) | 1080 | 18.71 (17.70–19.71) | < 0.001 |
| HR HPV | 1106 | 10.97 (10.36–11.58) | 1651 | 12.82 (12.24–13.40) | 964 | 16.70 (15.74–17.66) | < 0.001 |
| LR HPV | 169 | 1.68 (1.43–1.93) | 267 | 2.07 (1.83–2.32) | 216 | 3.74 (3.25–4.23) | < 0.001 |
| ANY HPV | 1433 | 14.21 (13.54–14.90) | 2248 | 17.46 (16.80–18.11) | 1499 | 25.97 (24.83–27.10) | < 0.001 |
4vHPV: 4-valent HPV types including HPV 6, 11, 16, and 18; 9vHPV: 9-valent HPV types including HPV 6, 11, 16, 18, 31, 33, 45, 52, and 58; HR HPV: high risk HPV types including HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, and cp8304; LR HPV: low risk HPV types including HPV 6, 11, 42, 43, and 44. Any HPV: any of the 21 HPV types mentioned above