Table 4.
Results of ROC analysis separated by TG/TL
| TG/TL 1 | TG/TL 2 | TG/TL 3 | ||||
|---|---|---|---|---|---|---|
| AUC (95%-CI) | Optimal cut-off value | AUC (95%-CI) | Optimal cut-off value | AUC (95%-CI) | Optimal cut-off value | |
| Metabolic parameters | ||||||
| MTV | 0.92 (0.74 to 1.0) | > 80 ml | 0.71 (0.44 to 0.99) | > 160 ml | 0.85 (0.69 to 1.0) | > 410 ml |
| SUVmax | 0.47 (0.1 to 0.86) | > 7.5 | 0.61 (0.29 to 0.94) | > 13.9 | 0.67 (0.43 to 0.91) | > 13.8 |
| SUVmean | 0.39 (0.0 to 0.76) | > 3.3 | 0.73 (0.49 to 0.97) | > 6.6 | 0.69 (0.46 to 0.93) | > 5.9 |
| SUVpeak | 0.42 (0.0 to 0.79) | > 5.3 | 0.6 (0.28 to 0.92) | > 12.3 | 0.71 (0.48 to 0.94) | > 12.6 |
| TLG | 0.89 (0.7 to 1.0) | > 320 ml | 0.66 (0.38 to 0.93) | > 890 ml | 0.85 (0.69 to 1.0) | > 2800 ml |
| Heterogeneity parameters | ||||||
| ASP | 0.78 (0.49 to 1.0) | > 137% | 0.5 (0.2 to 0.8) | > 90% | 0.7 (0.48 to 0.93) | > 235% |
| Entropy | 0.61 (0.27 to 0.95) | < 5.9 | 0.53 (0.22 to 0.84) | < 5.82 | 0.51 (0.25 to 0.77) | < 5.73 |
| Contrast | 0.78 (0.51 to 1.0) | < 39 | 0.54 (0.24 to 0.85) | < 17.6 | 0.61 (0.35 to 0.87) | < 19 |
| Local homogeneity | 0.67 (0.34 to 1.0) | > 21.8 | 0.43 (0.11 to 0.75) | > 23.3 | 0.64 (0.38 to 0.9) | > 30.4 |
| Energy | 0.58 (0.23 to 0.93) | > 0.37 | 0.54 (0.23 to 0.85) | > 0.41 | 0.48 (0.22 to 0.75) | > 0.51 |
| CSH | 0.33 (0.0 to 0.67) | > 0.52 | 0.63 (0.32 to 0.94) | > 0.44 | 0.51 (0.25 to 0.77) | > 0.41 |
TG/TL treatment group / level, 95%-CI 95%-confidence interval, MTV metabolic tumor volume, TLG total lesion glycolysis, ASP asphericity, CSH cumulative SUV-volume histograms