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Cumulative p24 (log10) viral concentrations in HIV-exposed rectal explants with either fresh 50% WS or SP were similar by the end of the 2-week assay (odds ratio 1.06–0.93, 95% CI). In conditions of fresh 50% WS, the EC50 was reached at 7.7 days following 102 TCID50 infection compared with the SP and control (10–11 days) (p = .02). At day 14, there were no significant differences in p24 with low to high TCID50 exposure. Mean ± SD plotted with nonlinear curve.
